The overall strategy of Prof Gill’s research is to study the relationships between phenotype and genotype in three key neuropsychiatric disorders; Psychoses, Autism and ADHD. Step one, gene hunting, is highly multidisciplinary and involves ascertaining large family and individual case samples and measuring clinical, neuropsychological, neurophysiological and neuroimaging phenotypes, and relating these to genotype at candidate genes and regions. We have developed a series of large and highly valuable family and individual case resources over the last ten years. Whole genome association approaches are underway or are planned. Step two, functional genomics, involves the focused examination of the function of demonstrated candidate genes, and their specific involvement in disease aetiology.
